Smc3 is required for mouse embryonic and adult hematopoiesis

Keyphrases

• Acute Myeloid Leukemia 11%
• Adult Hematopoiesis 100%
• Adult Mice 11%
• Bone Marrow Cells 11%
• Cell Population 11%
• Chromatin Modification 11%
• CKit 11%
• Cohesin Complex 11%
• Colony Forming Units 11%
• Competitive Disadvantage 11%
• Compound Heterozygous mutation 11%
• DNA Methyltransferase 3B (DNMT3B) 11%
• Dominant Negative 11%
• Dominant-negative Effect 11%
• Embryogenesis 11%
• Embryonic Hematopoiesis 100%
• Engraftment 11%
• Expression Change 11%
• Function Effect 11%
• Haploinsufficiency 33%
• Haploinsufficient 11%
• Hematopoietic Failure 11%
• Hematopoietic Stress 11%
• Homozygous Deletion 11%
• Loss Function 11%
• Lymphoid Lineage 11%
• Meiosis 11%
• Methylcellulose 11%
• Missense mutation 22%
• Mitosis 11%
• Mouse Model 11%
• Myeloid Cells 11%
• Myeloid Lineage 11%
• Myeloid Malignancies 11%
• Phenocopy 11%
• Sister Chromatids 11%
• SMC3 100%
• Steady-state Conditions 11%
• Transplantation 11%

Biochemistry, Genetics and Molecular Biology

• Chromatin 25%
• Cohesin 25%
• Embryogenesis 25%
• Haploinsufficiency 75%
• Hematopoiesis 100%
• Meiosis 25%
• Methyl Cellulose 25%
• Missense Mutation 50%
• Mitosis 25%
• Mouse Model 25%
• Myeloid 100%
• Phenocopy 25%
• Sister Chromatid 25%
• SMC3 100%
• Steady State 25%

Immunology and Microbiology

• Bone Marrow Cell 25%
• Cell Population 25%
• Chromatin 25%
• Embryo Development 25%
• Engraftment 25%
• Haploinsufficiency 75%
• Hematopoiesis 100%
• Lineages 25%
• Meiosis 25%
• Missense Mutation 50%
• Mitosis 25%
• Mouse Model 25%
• Myeloid 100%
• Sister Chromatid 25%
• Steady State 25%