Small cell lung cancer: Clinical practice guidelines in oncology

  • Gregory P. Kalemkerian
  • , Wallace Akerley
  • , Paul Bogner
  • , Hossein Borghaei
  • , Laura QM Chow
  • , Robert J. Downey
  • , Leena Gandhi
  • , Apar Kishor P. Ganti
  • , Ramaswamy Govindan
  • , John C. Grecula
  • , James Hayman
  • , Rebecca Suk Heist
  • , Leora Horn
  • , Thierry Jahan
  • , Marianna Koczywas
  • , Billy W. Loo
  • , Robert E. Merritt
  • , Cesar A. Moran
  • , Harvey B. Niell
  • , Janis O'Malley
  • Jyoti D. Patel, Neal Ready, Charles M. Rudin, Charles C. Williams, Kristina Gregory, Miranda Hughes

Research output: Contribution to journalArticlepeer-review

Abstract

Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.

Original languageEnglish
Pages (from-to)78-98
Number of pages21
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2013

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