Small and large bowel dysfunction

Deborah C. Rubin

doi:10.1007/978-1-59259-963-9_56

Small and large bowel dysfunction

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The study of inflammatory bowel diseases (IBD) has advanced greatly, with the identification of the first disease susceptibility gene for Crohn's disease, the tentative identification of other susceptibility loci for IBD, the creation of new animal models of IBD using gene knock out and transgenic technology, and the application of cellular and molecular techniques to develop novel therapies for IBD. This chapter summarizes the important molecular and genetic developments relevant to the study of IBD, celiac sprue, lactase deficiency, glucose-galactose malabsorption, and abetalipoproteinemia as several prominent examples of how molecular technology can help advance the practice of gastrointestinal medicine.

Original language	English
Title of host publication	Principles of Molecular Medicine
Publisher	Humana Press
Pages	581-589
Number of pages	9
ISBN (Print)	9781588292025
DOIs	https://doi.org/10.1007/978-1-59259-963-9_56
State	Published - 2006

Keywords

Abetalipoproteinemia
Chrohn's disease
celiac sprue
glucose-galactose malabsorption
inflammatory bowel diseases (IBD)
lactase deficiency
ulcerative colitis

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10.1007/978-1-59259-963-9_56

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AB - The study of inflammatory bowel diseases (IBD) has advanced greatly, with the identification of the first disease susceptibility gene for Crohn's disease, the tentative identification of other susceptibility loci for IBD, the creation of new animal models of IBD using gene knock out and transgenic technology, and the application of cellular and molecular techniques to develop novel therapies for IBD. This chapter summarizes the important molecular and genetic developments relevant to the study of IBD, celiac sprue, lactase deficiency, glucose-galactose malabsorption, and abetalipoproteinemia as several prominent examples of how molecular technology can help advance the practice of gastrointestinal medicine.

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ER -

Small and large bowel dysfunction

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Keywords

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