Slit proteins, potential endogenous modulators of inflammation

Necat Havlioglu, Liya Yuan, Hao Tang, Jane Y. Wu

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Recent studies suggest that molecules important for guiding neuronal migration and axon path-finding also play a role in modulating leukocyte chemotaxis. Neuronal migration and leukocyte chemotaxis may share some common regulatory mechanisms. Intracellular signal transduction mechanisms guiding neuronal migration and leukocyte chemotaxis are beginning to be elucidated. Studying molecular mechanisms modulating cell migration may provide new insights into understanding of endogenous inhibitors of inflammation.

Original languageEnglish
Pages (from-to)486-495
Number of pages10
JournalJournal of NeuroVirology
Volume8
Issue number6
DOIs
StatePublished - Dec 2002

Keywords

  • Axon guidance
  • Inflammation
  • Neuronal migration
  • Roundabout
  • Signal transduction
  • Slit

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