Sleepwalking stem cells

Jeffrey A. Magee

doi:10.1182/blood-2017-02-769059

Sleepwalking stem cells

Research output: Contribution to journal › Comment/debate

Abstract

In this issue of Blood, Bernitz et al show that granulocyte colony-stimulating factor (G-CSF) selectively mobilizes nondividing hematopoietic stem cells (HSCs).¹ A majority of the HSCs remain quiescent after mobilization and ultimately return to the bone marrow without dividing. Thus, G-CSF does not uniformly drive adult HSCs into cycle.

Original language	English
Pages (from-to)	1887-1888
Number of pages	2
Journal	Blood
Volume	129
Issue number	14
DOIs	https://doi.org/10.1182/blood-2017-02-769059
State	Published - Apr 6 2017

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title = "Sleepwalking stem cells",

abstract = "In this issue of Blood, Bernitz et al show that granulocyte colony-stimulating factor (G-CSF) selectively mobilizes nondividing hematopoietic stem cells (HSCs).1 A majority of the HSCs remain quiescent after mobilization and ultimately return to the bone marrow without dividing. Thus, G-CSF does not uniformly drive adult HSCs into cycle.",

author = "Magee, {Jeffrey A.}",

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AB - In this issue of Blood, Bernitz et al show that granulocyte colony-stimulating factor (G-CSF) selectively mobilizes nondividing hematopoietic stem cells (HSCs).1 A majority of the HSCs remain quiescent after mobilization and ultimately return to the bone marrow without dividing. Thus, G-CSF does not uniformly drive adult HSCs into cycle.

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U2 - 10.1182/blood-2017-02-769059

DO - 10.1182/blood-2017-02-769059

M3 - Comment/debate

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SN - 0006-4971

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SP - 1887

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JO - Blood

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Sleepwalking stem cells

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