Sleep Disturbances and Chronic Pain in People with HIV: Implications for HIV-Associated Neurocognitive Disorders

Shameka L. Cody, Joanna M. Hobson, Shannon R. Gilstrap, S. Justin Thomas, David Galinat, Burel R. Goodin

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Purpose of Review: Antiretroviral therapy has significantly reduced morbidity and mortality in people with HIV. Despite being virally suppressed, sleep disturbances, chronic pain, and neurocognitive impairments persist which can negatively impact quality of life for people with HIV. This article presents relevant literature related to sleep disturbances and chronic pain in people with HIV. The potential impact of these comorbidities on cognition is discussed with implications for managing HIV-associated neurocognitive disorder (HAND). Recent Findings: People with HIV and chronic pain report greater insomnia and depressive symptoms compared to those without chronic pain. The neurotoxic effects of HIV itself and sleep and chronic pain induced inflammation can contribute to poorer cognitive outcomes. Summary: Sleep disturbances and chronic pain are prevalent conditions in people with HIV that may perpetuate the development and exacerbation of HAND. Sleep and pain interventions may preserve cognitive function and improve quality of life for people aging with HIV.

Original languageEnglish
Pages (from-to)124-131
Number of pages8
JournalCurrent Sleep Medicine Reports
Volume8
Issue number4
DOIs
StatePublished - Dec 2022

Keywords

  • Aging
  • Chronic pain
  • Cognitive impairment
  • HIV
  • Sleep disturbances

Fingerprint

Dive into the research topics of 'Sleep Disturbances and Chronic Pain in People with HIV: Implications for HIV-Associated Neurocognitive Disorders'. Together they form a unique fingerprint.

Cite this