@article{2d3e32a8fc644de6a716e904aff999a4,
title = "Sleep-disordered breathing is common among term and near term infants in the NICU",
abstract = "Objective: Among older infants and children, sleep-disordered breathing (SDB) has negative neurocognitive consequences. We evaluated the frequency and potential impact of SDB among newborns who require intensive care. Study Design: Term and near-term newborns at risk for seizures underwent 12-h attended polysomnography in the neonatal intensive care unit (NICU). Bayley Scales of Infant Development, third edition (Bayley-III) were administered at 18-22 months. Result: The 48 newborns (EGA 39.3 ± 1.6) had a median pediatric apnea-hypopnea index (AHI) of 10.1 (3.3-18.5) and most events were central (vs obstructive). Maternal and prenatal factors were not associated with AHI. Moreover, neonatal PSG results were not associated with Bayley-III scores (P > 0.05). Conclusion: SDB is common among term and near-term newborns at risk for seizures. Follow-up at ages when more nuanced testing can be performed may be necessary to establish whether neonatal SDB is associated with long-term neurodevelopmental disability.",
keywords = "epidemiology, neonatal pulmonary medicine, sleep medicine",
author = "Meerkov, {Meera S.} and Fauziya Hassan and Chervin, {Ronald D.} and Barks, {John D.} and Carlson, {Martha D.} and Shellhaas, {Ren{\'e}e A.}",
note = "Funding Information: Meera Meerkov and Martha Carlson: The authors declare no conflict of interest. Fauziya Hassan: Research funding from Jazz Pharmaceuticals and on national advisory board for Biogen for Spinraza. Ronald Chervin: Employment by Michigan Medicine, Sleep Disorders Center, and Department of Neurology (which had no role in designing the study, collection or analysis of data, or decision to publish); research support from the NIH and Michigan Medicine; innovations copyrighted, patented, or patent pending by University of Michigan for assessment or treatment of obstructive sleep apnea and other sleep disorders; Pediatric Sleep Questionnaire licensed by University of Michigan to Zansors; service on boards of directors, American Academy of Sleep Medicine, Associated Professional Sleep Societies, International Pediatric Sleep Association, and the non-profit Sweet Dreamzzz, Inc; editor, Cambridge University Press; editor and author, UpToDate. John Barks: Dr. Barks is employed by the University of Michigan Health System, Department of Pediatrics. Dr. Barks receives research grant support from the National Institutes of Health and the University of Michigan Department of Pediatrics. Ren{\'e}e A. Shellhaas: Dr. Shellhaas is employed by the University of Michigan Health System, Department of Pediatrics. Dr. Shellhaas receives research grant support from the Patient-Centered Outcomes Research Institute (PCORI), the National Institutes of Health, the American Sleep Medicine Foundation, the Pediatric Epilepsy Research Foundation, and the University of Michigan Department of Pediatrics & Communicable Diseases. She serves on the editorial boards of Funding Information: This work was supported by NIH (5K23HD068402). Publisher Copyright: {\textcopyright} 2019 Wiley Periodicals, Inc.",
year = "2019",
month = may,
doi = "10.1002/ppul.24266",
language = "English",
volume = "54",
pages = "557--562",
journal = "Pediatric Pulmonology",
issn = "8755-6863",
number = "5",
}