Skeletal muscle imaging in neuromuscular disease

Neil G. Simon, Yu Ichi Noto, Craig M. Zaidman

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


Skeletal muscle imaging is increasingly used as a complement to clinical and electrophysiological examination in neuromuscular disease. Ultrasound and MRI have developed as the modalities of choice, each with strengths and limitations. Characteristic changes of muscle denervation and myopathy are seen on imaging which may delineate the nature of the disease process or help guide muscle biopsy. Identifying patterns of muscle involvement in hereditary myopathies may inform genetic testing. This review discusses skeletal muscle imaging in neuromuscular disease focusing on practical applications of current and emerging ultrasound and MRI techniques.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of Clinical Neuroscience
StatePublished - Nov 1 2016


  • Denervation
  • MRI
  • Muscle imaging
  • Myopathy
  • Neuromuscular disease
  • Ultrasound


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