Site-targeted acoustic contrast agent detects molecular expression of tissue factor after balloon angioplasty

Christopher S. Hall, Dana R. Abendschein, David E. Scherrer, Michael J. Scott, Jon N. Marsh, Samuel A. Wickline, Gregory M. Lanza

Research output: Contribution to journalConference article

Abstract

The concept of molecular imaging and localization of carotid arteries' tissue factor in vivo using a new, nanoparticulate emulsion is demonstrated. The enhancement of the visualization of the molecular expression of tissue factor could prove to be a prognostically important predictor of subsequent restenosis. Moreover, with the incorporation of specific drug treatments into the nanoparticulate contrast agent, ultrasonic molecular imaging may yield reliable detection and quantification of nascent pathologies and facilitate targeted drug therapy.

Original languageEnglish
Pages (from-to)325-332
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3982
StatePublished - Jan 1 2000
EventMedical Imaging 2000: Ultrasonic Imaging and Signal Processing - San Diego, CA, USA
Duration: Feb 16 2000Feb 17 2000

Fingerprint Dive into the research topics of 'Site-targeted acoustic contrast agent detects molecular expression of tissue factor after balloon angioplasty'. Together they form a unique fingerprint.

Cite this