TY - JOUR
T1 - Single neurons in posterior parietal cortex of monkeys encode cognitive set
AU - Stoet, Gijsbert
AU - Snyder, Lawrence H.
N1 - Funding Information:
We thank Justin Baker and David Van Essen for help with the MRI anatomy, and we thank several anonymous reviewers. This study was supported by the Otto-Hahn Fellowship of the Max-Planck Society (to G.S.), the NIH, and the EJLB Foundation.
PY - 2004/6/24
Y1 - 2004/6/24
N2 - The primate posterior parietal cortex (PPC), part of the dorsal visual pathway, is best known for its role in encoding salient spatial information. Yet there are indications that neural activity in the PPC can also be modulated by nonspatial task-related information. In this study, we tested whether neurons in the PPC encode signals related to cognitive set, that is, the preparation to perform a particular task. Cognitive set has previously been associated with the frontal cortex but not the PPC. In this study, monkeys performed a cognitive set shifting paradigm in which they were cued in advance to apply one of two different task rules to the subsequent stimulus on every trial. Here we show that a subset of neurons in the PPC, concentrated in the lateral bank of the intraparietal sulcus and on the angular gyrus, responds selectively to cues for different task rules.
AB - The primate posterior parietal cortex (PPC), part of the dorsal visual pathway, is best known for its role in encoding salient spatial information. Yet there are indications that neural activity in the PPC can also be modulated by nonspatial task-related information. In this study, we tested whether neurons in the PPC encode signals related to cognitive set, that is, the preparation to perform a particular task. Cognitive set has previously been associated with the frontal cortex but not the PPC. In this study, monkeys performed a cognitive set shifting paradigm in which they were cued in advance to apply one of two different task rules to the subsequent stimulus on every trial. Here we show that a subset of neurons in the PPC, concentrated in the lateral bank of the intraparietal sulcus and on the angular gyrus, responds selectively to cues for different task rules.
UR - http://www.scopus.com/inward/record.url?scp=2942722403&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2004.06.003
DO - 10.1016/j.neuron.2004.06.003
M3 - Article
C2 - 15207244
AN - SCOPUS:2942722403
SN - 0896-6273
VL - 42
SP - 1003
EP - 1012
JO - Neuron
JF - Neuron
IS - 6
ER -