TY - JOUR
T1 - Single-lung transplantation in pulmonary emphysema
AU - Sleiman, Charles
AU - Mal, Hervé
AU - Andreassian, Bernard
AU - Pariente, René
AU - Grossman, R. F.
AU - Maurer, J.
AU - Patterson, G. A.
PY - 1990/8/23
Y1 - 1990/8/23
N2 - To the Editor: In the March 15 issue of the Journal, Grossman et al. reported the results of single-lung transplantation for bilateral pulmonary fibrosis.1 We found their data very interesting, but we disagree with their conclusion that single-lung transplantation is not suitable for patients with emphysema because ventilation may shift to the native emphysematous lung, whereas blood flow will move preferentially to the implant, resulting in an intrapulmonary shunting. Between March 1988 and March 1990, we performed single-lung transplantation for end-stage pulmonary diseases in 14 patients. Eleven had severe pulmonary emphysema. Serial perfusion and ventilation scanning were performed one.
AB - To the Editor: In the March 15 issue of the Journal, Grossman et al. reported the results of single-lung transplantation for bilateral pulmonary fibrosis.1 We found their data very interesting, but we disagree with their conclusion that single-lung transplantation is not suitable for patients with emphysema because ventilation may shift to the native emphysematous lung, whereas blood flow will move preferentially to the implant, resulting in an intrapulmonary shunting. Between March 1988 and March 1990, we performed single-lung transplantation for end-stage pulmonary diseases in 14 patients. Eleven had severe pulmonary emphysema. Serial perfusion and ventilation scanning were performed one.
UR - http://www.scopus.com/inward/record.url?scp=0025074418&partnerID=8YFLogxK
U2 - 10.1056/NEJM199008233230816
DO - 10.1056/NEJM199008233230816
M3 - Letter
C2 - 2377183
AN - SCOPUS:0025074418
SN - 0028-4793
VL - 323
SP - 551
EP - 552
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 8
ER -