Single-lung transplantation in pulmonary emphysema

Charles Sleiman, Hervé Mal, Bernard Andreassian, René Pariente, R. F. Grossman, J. Maurer, G. A. Patterson

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: In the March 15 issue of the Journal, Grossman et al. reported the results of single-lung transplantation for bilateral pulmonary fibrosis.1 We found their data very interesting, but we disagree with their conclusion that single-lung transplantation is not suitable for patients with emphysema because ventilation may shift to the native emphysematous lung, whereas blood flow will move preferentially to the implant, resulting in an intrapulmonary shunting. Between March 1988 and March 1990, we performed single-lung transplantation for end-stage pulmonary diseases in 14 patients. Eleven had severe pulmonary emphysema. Serial perfusion and ventilation scanning were performed one.

Original languageEnglish
Pages (from-to)551-552
Number of pages2
JournalNew England Journal of Medicine
Issue number8
StatePublished - Aug 23 1990


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