Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

Keyphrases

• Activation Program 33%
• Autoimmune Diabetes 100%
• Autoimmune Disease 33%
• Autoimmune Process 33%
• Autoimmunity 33%
• Biological Function 33%
• Cell Population 33%
• Cellular Complexity 100%
• Cytotoxic CD8+ T Cells 33%
• Diabetic 33%
• Immune Cells 33%
• Immune Parameters 33%
• Infiltrating Cells 33%
• Inflammatory State 33%
• Islet 100%
• Macrophage Populations 33%
• Microenvironment 33%
• Molecular Signature 33%
• Murine Islets 100%
• Non-obese Diabetic Mice 33%
• Regulatory Cells 33%
• Resident Macrophages 33%
• Single-cell Atlas 33%
• Single-cell RNA Sequencing (scRNA-seq) 100%
• Stepwise Activation 33%
• Target Organ 33%
• Transcriptional Heterogeneity 33%

Immunology and Microbiology

• Autoimmune Diabetes 100%
• Autoimmune Disease 33%
• Autoimmunity 66%
• Biological Functions 33%
• CD4 33%
• Cell Population 66%
• Cytotoxic T-Cell 33%
• Immunocompetent Cell 66%
• Macrophage 66%
• Myeloid 33%
• Nonobese Diabetic Mouse 33%
• Regulatory Cell 33%
• RNA Sequence 100%
• Target Organ 33%