Studies in single cell transcriptomics have significantly expanded our understanding of tumor biology, including recent analyses in head and neck squamous cell carcinoma. Here, we focus on the role of a partial epithelial-to-mesenchymal (EMT) program in these tumors, with discussion of its dynamics, regulation, and implications for diagnostic and therapeutic approaches.

Original languageEnglish
Article numbere1448244
JournalMolecular and Cellular Oncology
Issue number3
StatePublished - May 4 2018


  • EMT
  • head and neck cancer
  • metastasis
  • single cell sequencing


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