Simultaneous MR Acquisition of Arterial and Brain Signal‐Time Curves

William H. Perman, Mokhtar H. Gado, Kenneth B. Larson, Joel S. Perlmutter

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Regional cerebral blood flow (rCBF) provides important information about local neuronal functional and cerebrovascular status. Determination of rCBF requires sequential measurements of tracer concentration in arterial blood and brain tissue unless the tracer is trapped in the brain in proportion to rCBF. Since gadopentate dimeglumine is not trapped within brain tissue, we have developed the simultaneous dual FLASH pulse sequence (SDFLASH) which sequentially measures the MR signal change in both the internal carotid artery and brain parenchyma simultaneously during the passage of a bolus of paramagnetic contrast material.© 1992 Academic Press,Inc.

Original languageEnglish
Pages (from-to)74-83
Number of pages10
JournalMagnetic resonance in medicine
Issue number1
StatePublished - Nov 1992


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