Simplification of the research diagnosis of HIV-associated sensory neuropathy

Scott R. Evans, David B. Clifford, Douglas W. Kitch, Karl Goodkin, Giovanni Schifitto, Justin C. McArthur, David M. Simpson

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Peripheral neuropathy (PN) is the most common neurological complication of HIV infection, affecting over one third of patients. The research diagnosis of PN is complicated by the need for expensive, time-consuming, and noxious diagnostic tests. We investigated whether nerve conduction studies (NSC) and quantitative sensory tests (QST) provide added value for the diagnosis of PN for research purposes or whether the easily obtainable clinical measures (sensory and motor symptoms, sensitivity to pain and vibration, tendon reflexes, motor function) are sufficient.

Original languageEnglish
Pages (from-to)434-439
Number of pages6
JournalHIV Clinical Trials
Issue number6
StatePublished - Nov 2008


  • Nerve conduction
  • Peripheral neuropathy
  • Quantitative tests
  • Sensory nuropathy


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