Significance of Studying Circulating Tumor Cells

Ram H. Datar, Zheng Ao, Richard J. Cote

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Circulating Tumor Cells (CTC) are tumor cells released into blood. They are considered the pivotal component of the metastatic cascade and are being extensively studied only in the last decade or so. Understanding the biological and clinical impact of CTC is likely to reveal important information of the metastatic process and contribute to better management of cancer. We briefly discuss here the current clinical utility of CTC and their emerging clinical applications.

Original languageEnglish
Title of host publicationCurrent Cancer Research
PublisherSpringer Nature
Number of pages13
StatePublished - 2016

Publication series

NameCurrent Cancer Research
ISSN (Print)2199-2584
ISSN (Electronic)2199-2592


  • Circulating cancer stem cells
  • CTC culture
  • CTC genomics
  • Current and emerging clinical applications of CTC
  • Epithelial–mesenchymal transition (EMT)


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