A technique for intersubject averaging of positron emission tomographic images using stereotactic anatomical standardization was developed and tested in the context of functional brain mapping, using intrasubject pairs of blood flow images. Noise (control-control comparisons) was progressively suppressed by averaging, as predicted. Signal (stimulus-control comparisons) was stable in both magnitude and location. Signal:noise, therefore, rose steadily with averaging. 6 refs.

Original languageEnglish
Number of pages2
StatePublished - Dec 1 1987


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