Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.

Original languageEnglish
Pages (from-to)488-490
Number of pages3
JournalCell metabolism
Issue number3
StatePublished - Mar 7 2017


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