Should I Stay or Should I Go: A Clash of α-Cell Identity

Maria S. Remedi

doi:10.1016/j.cmet.2017.02.014

Should I Stay or Should I Go: A Clash of α-Cell Identity

Research output: Contribution to journal › Short survey › peer-review

Abstract

Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.

Original language	English
Pages (from-to)	488-490
Number of pages	3
Journal	Cell metabolism
Volume	25
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2017.02.014
State	Published - Mar 7 2017

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title = "Should I Stay or Should I Go: A Clash of α-Cell Identity",

abstract = "Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.",

author = "Remedi, {Maria S.}",

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T2 - A Clash of α-Cell Identity

AU - Remedi, Maria S.

PY - 2017/3/7

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N2 - Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.

AB - Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.

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DO - 10.1016/j.cmet.2017.02.014

M3 - Short survey

C2 - 28273469

AN - SCOPUS:85014578386

SN - 1550-4131

VL - 25

SP - 488

EP - 490

JO - Cell metabolism

JF - Cell metabolism

IS - 3

ER -

Should I Stay or Should I Go: A Clash of α-Cell Identity

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