TY - JOUR
T1 - Shiga toxin/verocytotoxin-producing escherichia coli infections
T2 - Practical Clinical Perspectives
AU - Davis, T. Keefe
AU - Van De Kar, Nicole C.A.J.
AU - Tarr, Phillip I.
N1 - Publisher Copyright:
© 2014 American Society for Microbiology. All rights reserved.
PY - 2014
Y1 - 2014
N2 - Escherichia coli strains that produce Shiga toxins/verotoxins are rare, but important, causes of human disease. They are responsible for a spectrum of illnesses that range from the asymptomatic to the life-threatening hemolyticuremic syndrome; diseases caused by E. coli belonging to serotype O157:H7 are exceptionally severe. Each illness has a fairly predictable trajectory, and good clinical practice at one phase can be inappropriate at other phases. Early recognition, rapid and definitive microbiology, and strategic selection of tests increase the likelihood of good outcomes. The best management of these infections consists of avoiding antibiotics, antimotility agents, and narcotics and implementing aggressive intravenous volume expansion, especially in the early phases of illness.
AB - Escherichia coli strains that produce Shiga toxins/verotoxins are rare, but important, causes of human disease. They are responsible for a spectrum of illnesses that range from the asymptomatic to the life-threatening hemolyticuremic syndrome; diseases caused by E. coli belonging to serotype O157:H7 are exceptionally severe. Each illness has a fairly predictable trajectory, and good clinical practice at one phase can be inappropriate at other phases. Early recognition, rapid and definitive microbiology, and strategic selection of tests increase the likelihood of good outcomes. The best management of these infections consists of avoiding antibiotics, antimotility agents, and narcotics and implementing aggressive intravenous volume expansion, especially in the early phases of illness.
UR - http://www.scopus.com/inward/record.url?scp=84949051361&partnerID=8YFLogxK
U2 - 10.1128/microbiolspec.EHEC-0025-2014
DO - 10.1128/microbiolspec.EHEC-0025-2014
M3 - Article
C2 - 26104210
AN - SCOPUS:84949051361
VL - 2
JO - Microbiology Spectrum
JF - Microbiology Spectrum
SN - 2165-0497
IS - 4
M1 - EHEC-0025-2014
ER -