Shear wave propagation of the ferret brain at multiple frequencies in vivo

Yuan Feng; Yulin Chang; Ruth J. Okamoto; Philip V. Bayly

doi:10.1115/IMECE2012-88374

Shear wave propagation of the ferret brain at multiple frequencies in vivo

Yuan Feng, Yulin Chang, Ruth J. Okamoto, Philip V. Bayly

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Mathematical modeling and computer simulations are widely used for understanding traumatic brain injury (TBI). However, accurate tissue parameters are needed, especially for the brain in vivo . In this study, we used the ferret as the animal model because it is the smallest mammal with a folded brain and significant white matter tracts. Magnetic resonance elastography (MRE) has proven useful for in vivo measurement of biological tissue properties. Mechanical properties of the ferret brain over a range of frequencies from 400-800 Hz were studied using MRE. Experiment results show both that storage and loss modulus increases with frequency and that dissipative effects in the white matter (characterized by the loss modulus G'') were significant larger than in gray matter.

Original language	English
Title of host publication	ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
Pages	779-785
Number of pages	7
DOIs	https://doi.org/10.1115/IMECE2012-88374
State	Published - 2012
Event	ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 - Houston, TX, United States Duration: Nov 9 2012 → Nov 15 2012

Publication series

Name	ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume	2

Conference

Conference	ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
Country/Territory	United States
City	Houston, TX
Period	11/9/12 → 11/15/12

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10.1115/IMECE2012-88374

Cite this

Feng, Y., Chang, Y., Okamoto, R. J., & Bayly, P. V. (2012). Shear wave propagation of the ferret brain at multiple frequencies in vivo. In ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 (pp. 779-785). (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 2). https://doi.org/10.1115/IMECE2012-88374

@inproceedings{ae8b6eacf68d456f8bf505630fab72d4,

title = "Shear wave propagation of the ferret brain at multiple frequencies in vivo",

abstract = "Mathematical modeling and computer simulations are widely used for understanding traumatic brain injury (TBI). However, accurate tissue parameters are needed, especially for the brain in vivo . In this study, we used the ferret as the animal model because it is the smallest mammal with a folded brain and significant white matter tracts. Magnetic resonance elastography (MRE) has proven useful for in vivo measurement of biological tissue properties. Mechanical properties of the ferret brain over a range of frequencies from 400-800 Hz were studied using MRE. Experiment results show both that storage and loss modulus increases with frequency and that dissipative effects in the white matter (characterized by the loss modulus G'') were significant larger than in gray matter.",

author = "Yuan Feng and Yulin Chang and Okamoto, {Ruth J.} and Bayly, {Philip V.}",

year = "2012",

doi = "10.1115/IMECE2012-88374",

language = "English",

isbn = "9780791845189",

series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)",

pages = "779--785",

booktitle = "ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012",

note = "ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 ; Conference date: 09-11-2012 Through 15-11-2012",

}

Feng, Y, Chang, Y, Okamoto, RJ & Bayly, PV 2012, Shear wave propagation of the ferret brain at multiple frequencies in vivo. in ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), vol. 2, pp. 779-785, ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012, Houston, TX, United States, 11/9/12. https://doi.org/10.1115/IMECE2012-88374

Shear wave propagation of the ferret brain at multiple frequencies in vivo. / Feng, Yuan; Chang, Yulin; Okamoto, Ruth J. et al.
ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012. 2012. p. 779-785 (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Shear wave propagation of the ferret brain at multiple frequencies in vivo

AU - Feng, Yuan

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AU - Okamoto, Ruth J.

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N2 - Mathematical modeling and computer simulations are widely used for understanding traumatic brain injury (TBI). However, accurate tissue parameters are needed, especially for the brain in vivo . In this study, we used the ferret as the animal model because it is the smallest mammal with a folded brain and significant white matter tracts. Magnetic resonance elastography (MRE) has proven useful for in vivo measurement of biological tissue properties. Mechanical properties of the ferret brain over a range of frequencies from 400-800 Hz were studied using MRE. Experiment results show both that storage and loss modulus increases with frequency and that dissipative effects in the white matter (characterized by the loss modulus G'') were significant larger than in gray matter.

AB - Mathematical modeling and computer simulations are widely used for understanding traumatic brain injury (TBI). However, accurate tissue parameters are needed, especially for the brain in vivo . In this study, we used the ferret as the animal model because it is the smallest mammal with a folded brain and significant white matter tracts. Magnetic resonance elastography (MRE) has proven useful for in vivo measurement of biological tissue properties. Mechanical properties of the ferret brain over a range of frequencies from 400-800 Hz were studied using MRE. Experiment results show both that storage and loss modulus increases with frequency and that dissipative effects in the white matter (characterized by the loss modulus G'') were significant larger than in gray matter.

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T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)

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BT - ASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012

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Y2 - 9 November 2012 through 15 November 2012

ER -

Shear wave propagation of the ferret brain at multiple frequencies in vivo

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