TY - GEN
T1 - Shear lag sutures
T2 - ASME 2016 International Mechanical Engineering Congress and Exposition, IMECE 2016
AU - Linderman, Stephen W.
AU - Kormpakis, Ioannis
AU - Gelberman, Richard H.
AU - Birman, Victor
AU - Wegst, Ulrike G.K.
AU - Thomopoulos, Stavros
AU - Genin, Guy M.
N1 - Publisher Copyright:
© 2016 by ASME.
PY - 2016
Y1 - 2016
N2 - Conventional surgical suture is mechanically limited by the ability of the suture to transfer load to tissue at suture anchor points. Sutures coated with adhesives can improve mechanical load transfer beyond the range of performance of existing suture methods, thereby strengthening orthopaedic repairs and decreasing the risk of failure. The mechanical properties of suitable adhesives were identified using a shear lag model. Examination of the design space for an optimal adhesive demonstrated requirements for strong adhesion and low stiffness to maximize strength. As a proof of concept, cyanoacrylate-coated sutures were used to perform a clinically relevant flexor digitorum profundus tendon repair in cadaver tissue. Even with this non-ideal adhesive, the maximum load resisted by repaired cadaveric canine flexor tendon increased by ∼ 17.0% compared to standard repairs without adhesive. To rapidly assess adhesive binding to tendon, we ad-ditionally developed a lap shear test method using bovine deep digital flexor tendons as the adherends. Further study is needed to develop a strongly adherent, compliant adhesive within the optimal design space described by the model.
AB - Conventional surgical suture is mechanically limited by the ability of the suture to transfer load to tissue at suture anchor points. Sutures coated with adhesives can improve mechanical load transfer beyond the range of performance of existing suture methods, thereby strengthening orthopaedic repairs and decreasing the risk of failure. The mechanical properties of suitable adhesives were identified using a shear lag model. Examination of the design space for an optimal adhesive demonstrated requirements for strong adhesion and low stiffness to maximize strength. As a proof of concept, cyanoacrylate-coated sutures were used to perform a clinically relevant flexor digitorum profundus tendon repair in cadaver tissue. Even with this non-ideal adhesive, the maximum load resisted by repaired cadaveric canine flexor tendon increased by ∼ 17.0% compared to standard repairs without adhesive. To rapidly assess adhesive binding to tendon, we ad-ditionally developed a lap shear test method using bovine deep digital flexor tendons as the adherends. Further study is needed to develop a strongly adherent, compliant adhesive within the optimal design space described by the model.
UR - http://www.scopus.com/inward/record.url?scp=85021687746&partnerID=8YFLogxK
U2 - 10.1115/IMECE2016-67522
DO - 10.1115/IMECE2016-67522
M3 - Conference contribution
AN - SCOPUS:85021687746
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
BT - Biomedical and Biotechnology Engineering
PB - American Society of Mechanical Engineers (ASME)
Y2 - 11 November 2016 through 17 November 2016
ER -