Shaping the p53 Response with Nucleoporins

Melanie L. Yarbrough; Michael A. White; Beatriz M.A. Fontoura

doi:10.1016/j.molcel.2012.11.027

Shaping the p53 Response with Nucleoporins

Melanie L. Yarbrough
, Michael A. White
, Beatriz M.A. Fontoura

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.

Original language	English
Pages (from-to)	665-666
Number of pages	2
Journal	Molecular cell
Volume	48
Issue number	5
DOIs	https://doi.org/10.1016/j.molcel.2012.11.027
State	Published - Dec 14 2012

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@article{1c8d1df07a214a99bfab898a5decfce7,

title = "Shaping the p53 Response with Nucleoporins",

abstract = "In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.",

author = "Yarbrough, \{Melanie L.\} and White, \{Michael A.\} and Fontoura, \{Beatriz M.A.\}",

note = "Funding Information: The authors are supported by grants from the NIH and CPRIT.",

year = "2012",

month = dec,

day = "14",

doi = "10.1016/j.molcel.2012.11.027",

language = "English",

volume = "48",

pages = "665--666",

journal = "Molecular cell",

issn = "1097-2765",

number = "5",

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TY - JOUR

T1 - Shaping the p53 Response with Nucleoporins

AU - Yarbrough, Melanie L.

AU - White, Michael A.

AU - Fontoura, Beatriz M.A.

N1 - Funding Information: The authors are supported by grants from the NIH and CPRIT.

PY - 2012/12/14

Y1 - 2012/12/14

N2 - In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.

AB - In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.

UR - https://www.scopus.com/pages/publications/84870895266

U2 - 10.1016/j.molcel.2012.11.027

DO - 10.1016/j.molcel.2012.11.027

M3 - Short survey

C2 - 23244761

AN - SCOPUS:84870895266

SN - 1097-2765

VL - 48

SP - 665

EP - 666

JO - Molecular cell

JF - Molecular cell

IS - 5

ER -

Shaping the p53 Response with Nucleoporins

Abstract

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