Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review

Maher M. Balkis; Lama Bazzi; Ali Taher; Ziad Salem; Imad Uthman; Nadim Kanj; Fouad I. Boulos; Souha S. Kanj

doi:10.1080/00365540902978075

Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review

Maher M. Balkis, Lama Bazzi, Ali Taher, Ziad Salem, Imad Uthman, Nadim Kanj, Fouad I. Boulos, Souha S. Kanj

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9 Scopus citations

Abstract

We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.

Original language	English
Pages (from-to)	535-537
Number of pages	3
Journal	Scandinavian Journal of Infectious Diseases
Volume	41
Issue number	6-7
DOIs	https://doi.org/10.1080/00365540902978075
State	Published - 2009

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10.1080/00365540902978075

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title = "Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review",

abstract = "We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.",

author = "Balkis, {Maher M.} and Lama Bazzi and Ali Taher and Ziad Salem and Imad Uthman and Nadim Kanj and Boulos, {Fouad I.} and Kanj, {Souha S.}",

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AU - Balkis, Maher M.

AU - Bazzi, Lama

AU - Taher, Ali

AU - Salem, Ziad

AU - Uthman, Imad

AU - Kanj, Nadim

AU - Boulos, Fouad I.

AU - Kanj, Souha S.

PY - 2009

Y1 - 2009

N2 - We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.

AB - We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.

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DO - 10.1080/00365540902978075

M3 - Article

C2 - 19449255

AN - SCOPUS:72149103770

SN - 0036-5548

VL - 41

SP - 535

EP - 537

JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 6-7

ER -

Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review

Abstract

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