Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates

S. A. Norris; H. C.B. White; A. Tanenbaum; E. L. Williams; C. Cruchaga; L. Tian; R. E. Schmidt; J. S. Perlmutter

doi:10.1016/j.jneumeth.2021.109406

Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates

S. A. Norris, H. C.B. White, A. Tanenbaum, E. L. Williams, C. Cruchaga, L. Tian, R. E. Schmidt, J. S. Perlmutter

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	109406
Journal	Journal of Neuroscience Methods
Volume	366
DOIs	https://doi.org/10.1016/j.jneumeth.2021.109406
State	Published - Jan 15 2022

Keywords

Basal ganglia
MPTP
Monkey
Neurotoxicity
Striatum

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10.1016/j.jneumeth.2021.109406

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@article{3fc998812f4848a0aee28f99df2567b8,

title = "Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates",

keywords = "Basal ganglia, MPTP, Monkey, Neurotoxicity, Striatum",

author = "Norris, {S. A.} and White, {H. C.B.} and A. Tanenbaum and Williams, {E. L.} and C. Cruchaga and L. Tian and Schmidt, {R. E.} and Perlmutter, {J. S.}",

note = "Funding Information: This work was supported by NIH NINDS/NIA NS075321 , NS103957 , NS107281 , NS075527 , NS058714 , NS050425 , NS039913 , the Barnes Jewish Hospital Foundation (including the Elliot Stein Family Fund and Parkinson Disease Research Fund); the American Parkinson Disease Association (APDA) Advanced Research Center for Parkinson Disease at Washington University in St. Louis; the Greater St. Louis Chapter of the APDA; the Barbara & Sam Murphy Fund ; the McDonnell Center for Systems Neuroscience ; the Oertli Fund for Parkinson Disease Research , the Paula and Rodger Riney Fund for Parkinson disease research. ",

year = "2022",

month = jan,

day = "15",

doi = "10.1016/j.jneumeth.2021.109406",

language = "English",

volume = "366",

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TY - JOUR

T1 - Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates

AU - Norris, S. A.

AU - White, H. C.B.

AU - Tanenbaum, A.

AU - Williams, E. L.

AU - Cruchaga, C.

AU - Tian, L.

AU - Schmidt, R. E.

AU - Perlmutter, J. S.

N1 - Funding Information: This work was supported by NIH NINDS/NIA NS075321 , NS103957 , NS107281 , NS075527 , NS058714 , NS050425 , NS039913 , the Barnes Jewish Hospital Foundation (including the Elliot Stein Family Fund and Parkinson Disease Research Fund); the American Parkinson Disease Association (APDA) Advanced Research Center for Parkinson Disease at Washington University in St. Louis; the Greater St. Louis Chapter of the APDA; the Barbara & Sam Murphy Fund ; the McDonnell Center for Systems Neuroscience ; the Oertli Fund for Parkinson Disease Research , the Paula and Rodger Riney Fund for Parkinson disease research.

PY - 2022/1/15

Y1 - 2022/1/15

KW - Basal ganglia

KW - MPTP

KW - Monkey

KW - Neurotoxicity

KW - Striatum

UR - http://www.scopus.com/inward/record.url?scp=85118901835&partnerID=8YFLogxK

U2 - 10.1016/j.jneumeth.2021.109406

DO - 10.1016/j.jneumeth.2021.109406

M3 - Article

C2 - 34767855

AN - SCOPUS:85118901835

SN - 0165-0270

VL - 366

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

M1 - 109406

ER -

Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates

Keywords

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