TY - JOUR
T1 - Severe Acute Blood Loss Anemia in Jehovah's Witnesses Undergoing Cardiac Surgery
T2 - Single Academic Center Experience
AU - Helwani, Mohammad A.
AU - De Wet, Charl J.
AU - Pennington, Bethany
AU - Abdulnabi, Sami
AU - Moon, Marc R.
N1 - Funding Information:
None.
Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2023/4
Y1 - 2023/4
N2 - Objective: To determine the effect of severe acute blood loss anemia (ABLA) on postoperative outcomes in Jehovah's Witness (JW) patients undergoing cardiac surgery. Design: This was a retrospective cohort study of adult JW patients undergoing cardiac surgery requiring cardiopulmonary bypass (CPB) between January 1998 and December 2018 at Barnes-Jewish Hospital in St. Louis, Missouri. Setting: At a single tertiary academic center. Participants: Patients who were JWs undergoing cardiac surgery requiring CPB. Interventions: Patients were divided into the following 2 groups: JW patients who developed severe ABLA (defined as postoperative hematocrit level <21), and patients who did not develop severe ABLA. Measurements and Main Results: A total of 48 JW patients who underwent cardiac surgery between 2008 and 2018 were identified. Of these patients, 9 (18.8%) developed postoperative severe ABLA, and 39 (81.3%) did not. Severe ABLA was associated with increased postoperative mortality at 30-days, 90-days, and 1-year postoperatively, and a trend toward increased hospital length of stay. Conclusions: Severe ABLA after cardiac surgery was associated with higher mortality and a trend toward increased hospital length of stay among JW patients. More data are required to confirm the findings.
AB - Objective: To determine the effect of severe acute blood loss anemia (ABLA) on postoperative outcomes in Jehovah's Witness (JW) patients undergoing cardiac surgery. Design: This was a retrospective cohort study of adult JW patients undergoing cardiac surgery requiring cardiopulmonary bypass (CPB) between January 1998 and December 2018 at Barnes-Jewish Hospital in St. Louis, Missouri. Setting: At a single tertiary academic center. Participants: Patients who were JWs undergoing cardiac surgery requiring CPB. Interventions: Patients were divided into the following 2 groups: JW patients who developed severe ABLA (defined as postoperative hematocrit level <21), and patients who did not develop severe ABLA. Measurements and Main Results: A total of 48 JW patients who underwent cardiac surgery between 2008 and 2018 were identified. Of these patients, 9 (18.8%) developed postoperative severe ABLA, and 39 (81.3%) did not. Severe ABLA was associated with increased postoperative mortality at 30-days, 90-days, and 1-year postoperatively, and a trend toward increased hospital length of stay. Conclusions: Severe ABLA after cardiac surgery was associated with higher mortality and a trend toward increased hospital length of stay among JW patients. More data are required to confirm the findings.
KW - Jehovah's witness
KW - cardiac surgery
KW - postoperative complications
KW - severe acute blood loss anemia
KW - transfusion refusal
UR - http://www.scopus.com/inward/record.url?scp=85142691536&partnerID=8YFLogxK
U2 - 10.1053/j.jvca.2022.10.031
DO - 10.1053/j.jvca.2022.10.031
M3 - Article
C2 - 36435723
AN - SCOPUS:85142691536
SN - 1053-0770
VL - 37
SP - 513
EP - 518
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
IS - 4
ER -