Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases

Mary Allen Staat; Laura Patricia Stadler; Stephanie Donauer; Indi Trehan; Marilyn Rice; Shelia Salisbury

doi:10.1016/j.vaccine.2010.09.069

Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases

Mary Allen Staat, Laura Patricia Stadler, Stephanie Donauer, Indi Trehan, Marilyn Rice, Shelia Salisbury

Division of Emergency Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations.

Original language	English
Pages (from-to)	7947-7955
Number of pages	9
Journal	Vaccine
Volume	28
Issue number	50
DOIs	https://doi.org/10.1016/j.vaccine.2010.09.069
State	Published - Nov 23 2010

Keywords

Immunization
International adoption
Serology
Vaccine preventable diseases

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10.1016/j.vaccine.2010.09.069

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title = "Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases",

abstract = "Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations.",

keywords = "Immunization, International adoption, Serology, Vaccine preventable diseases",

author = "Staat, {Mary Allen} and Stadler, {Laura Patricia} and Stephanie Donauer and Indi Trehan and Marilyn Rice and Shelia Salisbury",

note = "Funding Information: Salary support to Dr. Stadler during this research was provided by Molecular Epidemiology Child Environmental Health NIEHS training grant 5-T32-ES010957-08 , through the Department of Environmental Health, Division of Biostatistics and Epidemiology, University of Cincinnati College of Medicine. Dr. Trehan is partly supported by NIH training grant 5-T32-HD049338-03 . ",

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AU - Donauer, Stephanie

AU - Trehan, Indi

AU - Rice, Marilyn

AU - Salisbury, Shelia

N1 - Funding Information: Salary support to Dr. Stadler during this research was provided by Molecular Epidemiology Child Environmental Health NIEHS training grant 5-T32-ES010957-08 , through the Department of Environmental Health, Division of Biostatistics and Epidemiology, University of Cincinnati College of Medicine. Dr. Trehan is partly supported by NIH training grant 5-T32-HD049338-03 .

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N2 - Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations.

AB - Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations.

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KW - Serology

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Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases

Abstract

Keywords

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