Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells

Peter L. Wang; Rafael S. Czepielewski; Gwendalyn J. Randolph

doi:10.1016/j.it.2021.01.008

Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells

Peter L. Wang
, Rafael S. Czepielewski
, Gwendalyn J. Randolph

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.

Original language	English
Pages (from-to)	180-182
Number of pages	3
Journal	Trends in Immunology
Volume	42
Issue number	3
DOIs	https://doi.org/10.1016/j.it.2021.01.008
State	Published - Mar 2021

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@article{f4cf6615b1a844e98de801800f23b489,

title = "Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells",

abstract = "The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.",

author = "Wang, \{Peter L.\} and Czepielewski, \{Rafael S.\} and Randolph, \{Gwendalyn J.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2021",

month = mar,

doi = "10.1016/j.it.2021.01.008",

language = "English",

volume = "42",

pages = "180--182",

journal = "Trends in Immunology",

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T1 - Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells

AU - Wang, Peter L.

AU - Czepielewski, Rafael S.

AU - Randolph, Gwendalyn J.

PY - 2021/3

Y1 - 2021/3

N2 - The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.

AB - The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.

UR - https://www.scopus.com/pages/publications/85100585221

U2 - 10.1016/j.it.2021.01.008

DO - 10.1016/j.it.2021.01.008

M3 - Short survey

C2 - 33563563

AN - SCOPUS:85100585221

SN - 1471-4906

VL - 42

SP - 180

EP - 182

JO - Trends in Immunology

JF - Trends in Immunology

IS - 3

ER -

Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells

Abstract

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