The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.

Original languageEnglish
Pages (from-to)180-182
Number of pages3
JournalTrends in Immunology
Issue number3
StatePublished - Mar 2021


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