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Senescence impairs direct conversion of human somatic cells to neurons
Chong Kui Sun
, Di Zhou
, Zhen Zhang
, Liming He
, Fan Zhang
, Xiaowei Wang
, Jie Yuan
, Qianming Chen
, Ling Gang Wu
, Qin Yang
Division of Cancer Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
23
Scopus citations
Overview
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Keyphrases
Direct Conversion
100%
Senescence
100%
Human Somatic Cells
100%
Neuronal Conversion
100%
Fibroblasts
66%
Induced Neurons
66%
Somatic Cells
33%
Receptor-mediated
33%
Transcription Factor
33%
Action Potential
33%
Human Fibroblast Cells
33%
Human Fibroblasts
33%
Cellular Senescence
33%
P53 Expression
33%
Human Epithelial Cells
33%
Forced Expression
33%
Neurotransmitter Receptors
33%
Transcriptional Analysis
33%
P16INK4a
33%
Human Telomerase Reverse Transcriptase (hTERT)
33%
P19Arf
33%
Neuronal Proteins
33%
Culture Stage
33%
Neuroscience
Somatic Cell
100%
Fibroblast
100%
Action Potential
25%
Transcription Factors
25%
Epithelial Cells
25%
P53
25%
Cellular Senescence
25%
Telomerase Reverse Transcriptase
25%
Neurotransmitter Receptor
25%
Biochemistry, Genetics and Molecular Biology
Somatic Cell
100%
Fibroblast
100%
P53
25%
Transcription Factors
25%
Action Potential
25%
P16
25%
Telomerase Reverse Transcriptase
25%
Neurotransmitter Receptor
25%