Self help for T cells

Eric Hailman, Paul M. Allen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A handful of agonist peptide-MHC complexes can evoke a sustained signal from the T cell receptor. A combination of mathematical models and imaging experiments suggests a key function for CD4 and endogenous (self) peptides in the generation of this sensitive response.

Original languageEnglish
Pages (from-to)780-783
Number of pages4
JournalNature immunology
Issue number8
StatePublished - Aug 2004


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