Abstract
A handful of agonist peptide-MHC complexes can evoke a sustained signal from the T cell receptor. A combination of mathematical models and imaging experiments suggests a key function for CD4 and endogenous (self) peptides in the generation of this sensitive response.
Original language | English |
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Pages (from-to) | 780-783 |
Number of pages | 4 |
Journal | Nature immunology |
Volume | 5 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2004 |