Selenium status, kwashiorkor and congestive heart failure

M. J. Manary, G. D. MacPherson, F. McArdle, M. J. Jackson, C. A. Hart

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Selenium deficiency is associated with congestive heart failure (CHF) in geographic areas where dietary selenium intake is low and in individuals receiving total parenteral nutrition. Among 66 children with kwashiorkor (including marasmic-kwashiorkor), those who developed CHF had lower serum selenium concentrations than those who did not (32.9 ± 8.3 vs 41.1 ± 11.9 μg/L, mean ± SD, p = 0.03). This association was independent of serum albumin and selenium status was not associated with severity of symptoms, anthropometric indices or HIV infection. Conclusion: This association raises the possibility that selenium may contribute to CHF in kwashiorkor.

Original languageEnglish
Pages (from-to)950-952
Number of pages3
JournalActa Paediatrica, International Journal of Paediatrics
Issue number8
StatePublished - Jan 1 2001


  • Heart failure
  • Kwashiorkor
  • Selenium


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