Selective cleavage and anticoagulant activity of a sulfated fucan: Stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity

Vitor H. Pomin, Mariana S. Pereira, Ana Paula Valente, Douglas M. Tollefsen, Mauro S.G. Pavão, Paulo A.S. Mourão

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Pharmacology, Toxicology and Pharmaceutical Science