Selection of controls in clinical trials: Introduction and conference summary

David H. Au, Mario Castro, Jerry A. Krishnan

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Understanding the strengths and weaknesses of the control group used in a randomized clinical trial is essential because comparisons of outcomes between the investigational and control groups form the basis of inferences regarding the safety and efficacy of the investigational treatment. For its 2007 International Conference, the American Thoracic Society (ATS) sponsored a scientific symposium in which the strengths and limitations of different types of control groups in clinical trials of pharmacotherapy, procedures, devices, and behavioral interventions were discussed. In this section, the co-chairs of this ATS symposium provide an overview of the presentations, including a brief historical perspective on the use of control groups in clinical trials.

Original languageEnglish
Pages (from-to)567-569
Number of pages3
JournalProceedings of the American Thoracic Society
Volume4
Issue number7
DOIs
StatePublished - Oct 2007

Keywords

  • Clinical trials
  • Control groups
  • Ethics

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