Seeing it through: Translational validation of new medical imaging modalities

Melissa B. Aldrich; Milton V. Marshall; Eva M. Sevick-Muraca; Greg Lanza; John Kotyk; Joseph Culver; Lihong V. Wang; Jashim Uddin; Brenda C. Crews; Lawrence J. Marnett; Joseph C. Liao; Chris Contag; James M. Crawford; Ken Wang; Bill Reisdorph; Henry Appelman; D. Kim Turgeon; Charles eyer; Tom Wang

doi:10.1364/BOE.3.000764

Seeing it through: Translational validation of new medical imaging modalities

Melissa B. Aldrich, Milton V. Marshall, Eva M. Sevick-Muraca, Greg Lanza, John Kotyk, Joseph Culver, Lihong V. Wang, Jashim Uddin, Brenda C. Crews, Lawrence J. Marnett, Joseph C. Liao, Chris Contag, James M. Crawford, Ken Wang, Bill Reisdorph, Henry Appelman, D. Kim Turgeon, Charles eyer, Tom Wang

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to "bridge the gap" between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.

Original language	English
Pages (from-to)	764-776
Number of pages	13
Journal	Biomedical Optics Express
Volume	3
Issue number	4
DOIs	https://doi.org/10.1364/BOE.3.000764
State	Published - Apr 1 2012

Access to Document

10.1364/BOE.3.000764

Cite this

Aldrich, M. B., Marshall, M. V., Sevick-Muraca, E. M., Lanza, G., Kotyk, J., Culver, J., Wang, L. V., Uddin, J., Crews, B. C., Marnett, L. J., Liao, J. C., Contag, C., Crawford, J. M., Wang, K., Reisdorph, B., Appelman, H., Kim Turgeon, D., eyer, C., & Wang, T. (2012). Seeing it through: Translational validation of new medical imaging modalities. Biomedical Optics Express, 3(4), 764-776. https://doi.org/10.1364/BOE.3.000764

@article{0cbd9ba834804dce9671633f1a756a83,

title = "Seeing it through: Translational validation of new medical imaging modalities",

abstract = "Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to {"}bridge the gap{"} between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.",

author = "Aldrich, {Melissa B.} and Marshall, {Milton V.} and Sevick-Muraca, {Eva M.} and Greg Lanza and John Kotyk and Joseph Culver and Wang, {Lihong V.} and Jashim Uddin and Crews, {Brenda C.} and Marnett, {Lawrence J.} and Liao, {Joseph C.} and Chris Contag and Crawford, {James M.} and Ken Wang and Bill Reisdorph and Henry Appelman and {Kim Turgeon}, D. and Charles eyer and Tom Wang",

year = "2012",

month = apr,

day = "1",

doi = "10.1364/BOE.3.000764",

language = "English",

volume = "3",

pages = "764--776",

journal = "Biomedical Optics Express",

issn = "2156-7085",

number = "4",

}

Aldrich, MB, Marshall, MV, Sevick-Muraca, EM, Lanza, G, Kotyk, J, Culver, J, Wang, LV, Uddin, J, Crews, BC, Marnett, LJ, Liao, JC, Contag, C, Crawford, JM, Wang, K, Reisdorph, B, Appelman, H, Kim Turgeon, D, eyer, C & Wang, T 2012, 'Seeing it through: Translational validation of new medical imaging modalities', Biomedical Optics Express, vol. 3, no. 4, pp. 764-776. https://doi.org/10.1364/BOE.3.000764

TY - JOUR

T1 - Seeing it through

T2 - Translational validation of new medical imaging modalities

AU - Aldrich, Melissa B.

AU - Marshall, Milton V.

AU - Sevick-Muraca, Eva M.

AU - Lanza, Greg

AU - Kotyk, John

AU - Culver, Joseph

AU - Wang, Lihong V.

AU - Uddin, Jashim

AU - Crews, Brenda C.

AU - Marnett, Lawrence J.

AU - Liao, Joseph C.

AU - Contag, Chris

AU - Crawford, James M.

AU - Wang, Ken

AU - Reisdorph, Bill

AU - Appelman, Henry

AU - Kim Turgeon, D.

AU - eyer, Charles

AU - Wang, Tom

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to "bridge the gap" between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.

AB - Medical imaging is an invaluable tool for diagnosis, surgical guidance, and assessment of treatment efficacy. The Network for Translational Research (NTR) for Optical Imaging consists of four research groups working to "bridge the gap" between lab discovery and clinical use of fluorescence- and photoacoustic-based imaging devices used with imaging biomarkers. While the groups are using different modalities, all the groups face similar challenges when attempting to validate these systems for FDA approval and, ultimately, clinical use. Validation steps taken, as well as future needs, are described here. The group hopes to provide translational validation guidance for itself, as well as other researchers.

UR - http://www.scopus.com/inward/record.url?scp=84863966250&partnerID=8YFLogxK

U2 - 10.1364/BOE.3.000764

DO - 10.1364/BOE.3.000764

M3 - Article

C2 - 22574264

AN - SCOPUS:84863966250

SN - 2156-7085

VL - 3

SP - 764

EP - 776

JO - Biomedical Optics Express

JF - Biomedical Optics Express

IS - 4

ER -

Seeing it through: Translational validation of new medical imaging modalities

Abstract

Access to Document

Other files and links

Fingerprint

Cite this