12 Scopus citations


We report on a patient with cranio-cervical dystonia injected with the new, lower protein formulation of botulinum toxin A who developed secondary resistance to this toxin. Subsequent injections with botulinum toxin B provided substantial reduction of blepharospasm. This is the first reported case of secondary resistance to the new preparation of botulinum toxin A.

Original languageEnglish
Pages (from-to)1098-1100
Number of pages3
JournalMovement Disorders
Issue number5
StatePublished - Sep 2002


  • Botulinum toxin A
  • Secondary resitance


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