Secondary localized sectoral keratoconjunctival amyloidosis from ocular trauma

Purpose: To report a case of unilateral localized sectoral conjunctival amyloidosis associated with corneal amyloidosis. Methods: Case report. Results: A 27-year-old woman with a history of ocular trauma presented with a limbus-based pink-yellow colored superonasal conjunctival lesion with adjacent superonasal sectoral corneal lattice-like changes. The lesion was monitored for 3 years with minimal enlargement, but conjunctival chalasis developed, which was bothersome to the patient. A conjunctival excisional biopsy confirmed the diagnosis of amyloidosis. Conclusions: To our knowledge, this is the first report of unilateral combined corneal and conjunctival amyloid deposition. Even more unusual was the sectoral distribution of the amyloid. This likely represents a local production and deposition of amyloid.