Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine

Amanda F. Cashen; Hollie Devine; John DiPersio

doi:10.1002/ajh.20626

Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine

Amanda F. Cashen, Hollie Devine, John DiPersio

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3 Scopus citations

Abstract

A 67-year-old man with acute myeloid leukemia (AML) was treated with low-dose decitabine. He achieved a complete remission (CR) after two cycles of therapy, and he remained in remission during 1 year of treatment. He developed recurrent AML after discontinuation of decitabine. He was retreated with decitabine and again achieved a CR, which has been maintained for 6 months. This case demonstrates that durable responses can occur upon retreatment with decitabine.

Original language	English
Pages (from-to)	543-545
Number of pages	3
Journal	American journal of hematology
Volume	81
Issue number	7
DOIs	https://doi.org/10.1002/ajh.20626
State	Published - Jul 1 2006

Keywords

Acute myeloid leukemia
Decitabine
Myelodysplastic syndromes

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10.1002/ajh.20626

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abstract = "A 67-year-old man with acute myeloid leukemia (AML) was treated with low-dose decitabine. He achieved a complete remission (CR) after two cycles of therapy, and he remained in remission during 1 year of treatment. He developed recurrent AML after discontinuation of decitabine. He was retreated with decitabine and again achieved a CR, which has been maintained for 6 months. This case demonstrates that durable responses can occur upon retreatment with decitabine.",

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AU - Devine, Hollie

AU - DiPersio, John

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N2 - A 67-year-old man with acute myeloid leukemia (AML) was treated with low-dose decitabine. He achieved a complete remission (CR) after two cycles of therapy, and he remained in remission during 1 year of treatment. He developed recurrent AML after discontinuation of decitabine. He was retreated with decitabine and again achieved a CR, which has been maintained for 6 months. This case demonstrates that durable responses can occur upon retreatment with decitabine.

AB - A 67-year-old man with acute myeloid leukemia (AML) was treated with low-dose decitabine. He achieved a complete remission (CR) after two cycles of therapy, and he remained in remission during 1 year of treatment. He developed recurrent AML after discontinuation of decitabine. He was retreated with decitabine and again achieved a CR, which has been maintained for 6 months. This case demonstrates that durable responses can occur upon retreatment with decitabine.

KW - Acute myeloid leukemia

KW - Decitabine

KW - Myelodysplastic syndromes

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Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine

Abstract

Keywords

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