Several research groups have begun mounting large, ambitious family studies to map genes for atherosclerosis, heart disease, and their major risk factors using whole genome linkage and/or disequilibrium scans. Some of the problems, pitfalls, and challenges of this exciting effort are examined and illustrated with lessons from an earlier mapping problem.

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalCurrent Atherosclerosis Reports
Issue number3
StatePublished - May 2002


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