Searching for novel therapeutics and targets: Insights from clinical trials

Anirban P. Mitra, Richard J. Cote

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Recent advances behind the understanding of the molecular mechanisms of bladder tumorigenesis have contributed towards the identification of molecules that can act as potential therapeutic targets for novel agents. Concurrently, this has also led to the understanding that effective therapy for superficial and invasive bladder cancers will entail a combination of therapeutic agents that target multiple tumorigenic pathways. Management of bladder cancer patients, as is the case in many other solid tumors, may witness radical transformations in the coming years as we translate our molecular understanding of the disease into novel clinical trial designs and screening techniques.

Original languageEnglish
Pages (from-to)341-343
Number of pages3
JournalUrologic Oncology: Seminars and Original Investigations
Issue number4
StatePublished - Jul 2007


  • Bladder cancer
  • Clinical trials
  • Cost-effectiveness
  • Novel therapeutics
  • Recurrence
  • Screening
  • Superficial tumors


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