@inproceedings{d35a1e5ba8204466a9ae91cccfce3dfc,
title = "Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe",
abstract = "A portable near infrared scanning polarization imaging unit with an optical fiber-based rectal probe, namely Photonic Finger, was designed and developed o locate the 3D position of abnormal prostate site inside normal prostate tissue. An inverse algorithm, Optical Tomography using Independent Component Analysis (OPTICA) was improved particularly to unmix the signal from targets (cancerous tissue) embedded in a turbid medium (normal tissue) in the backscattering imaging geometry. Photonic Finger combined with OPTICA was tested to characterize different target(s) inside different tissue medium, including cancerous prostate tissue embedded by large piece of normal tissue.",
keywords = "Independent Component Analysis (ICA), Photonic Finger (PF), backscattering, human prostate tissue, multiple angular view, optical fiber-based rectal probe, photon propagation model, receptor-target contrast agent, scanning optical polarization imaging, three-dimensional localization",
author = "Yang Pu and Wubao Wang and Guichen Tang and Yury Budansky and Mikhail Sharonov and Min Xu and Samuel Achilefu and Eastham, {James A.} and Alfano, {Robert R.}",
year = "2012",
doi = "10.1117/12.904254",
language = "English",
isbn = "9780819488633",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Optical Biopsy X",
note = "Optical Biopsy X ; Conference date: 24-01-2012 Through 25-01-2012",
}