TY - JOUR
T1 - Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008
T2 - A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology
AU - Levin, Bernard
AU - Lieberman, David A.
AU - McFarland, Beth
AU - Andrews, Kimberly S.
AU - Brooks, Durado
AU - Bond, John
AU - Dash, Chiranjeev
AU - Giardiello, Francis M.
AU - Glick, Seth
AU - Johnson, David
AU - Johnson, C. Daniel
AU - Levin, Theodore R.
AU - Pickhardt, Perry J.
AU - Rex, Douglas K.
AU - Smith, Robert A.
AU - Thorson, Alan
AU - Winawer, Sidney J.
N1 - Funding Information:
There also are a number of CTC trials currently in progress within the United States and Europe. Initial results from smaller screening trials utilizing 3D polyp detection by Cash et al 170 and Graser et al 171 have shown CTC performance characteristics similar to that of Pickhardt et al, providing at least a measure of independent validation for this screening technique. Also of particular interest is the recently completed ACRIN Study 6664: National CT Colonography Trial, which is sponsored and funded by the National Cancer Institute. The primary aim of this trial was to assess CTC performance for large adenomas and advanced neoplasia in a large screening cohort of 2500 patients across 15 institutions. State-of-the-art techniques included oral contrast tagging, colonic distention with automated carbon dioxide delivery, multidetector row CT (≥16 slice) with thin collimation, and both 2D and 3D polyp detection on dedicated CTC software systems. Preliminary findings announced at the 2007 annual meeting of ACRIN on September 28, 2007, were consistent with other recent studies using state-of-the-art techniques.
PY - 2008/5
Y1 - 2008/5
N2 - In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed among men and women and the second leading cause of death from cancer. CRC largely can be prevented by the detection and removal of adenomatous polyps, and survival is significantly better when CRC is diagnosed while still localized. In 2006 to 2007, the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology came together to develop consensus guidelines for the detection of adenomatous polyps and CRC in asymptomatic average-risk adults. In this update of each organization's guidelines, screening tests are grouped into those that primarily detect cancer early and those that can detect cancer early and also can detect adenomatous polyps, thus providing a greater potential for prevention through polypectomy. When possible, clinicians should make patients aware of the full range of screening options, but at a minimum they should be prepared to offer patients a choice between a screening test that primarily is effective at early cancer detection and a screening test that is effective at both early cancer detection and cancer prevention through the detection and removal of polyps. It is the strong opinion of these 3 organizations that colon cancer prevention should be the primary goal of screening.
AB - In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed among men and women and the second leading cause of death from cancer. CRC largely can be prevented by the detection and removal of adenomatous polyps, and survival is significantly better when CRC is diagnosed while still localized. In 2006 to 2007, the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology came together to develop consensus guidelines for the detection of adenomatous polyps and CRC in asymptomatic average-risk adults. In this update of each organization's guidelines, screening tests are grouped into those that primarily detect cancer early and those that can detect cancer early and also can detect adenomatous polyps, thus providing a greater potential for prevention through polypectomy. When possible, clinicians should make patients aware of the full range of screening options, but at a minimum they should be prepared to offer patients a choice between a screening test that primarily is effective at early cancer detection and a screening test that is effective at both early cancer detection and cancer prevention through the detection and removal of polyps. It is the strong opinion of these 3 organizations that colon cancer prevention should be the primary goal of screening.
UR - http://www.scopus.com/inward/record.url?scp=42949127635&partnerID=8YFLogxK
U2 - 10.1053/j.gastro.2008.02.002
DO - 10.1053/j.gastro.2008.02.002
M3 - Article
C2 - 18384785
AN - SCOPUS:42949127635
SN - 0016-5085
VL - 134
SP - 1570
EP - 1595
JO - Gastroenterology
JF - Gastroenterology
IS - 5
ER -