SCINTIGRAPHIC DETECTION OF ATHEROSCLEROTIC LESIONS AND VENOUS THROMBI IN MAN BY INDIUM-111-LABELLED AUTOLOGOUS PLATELETS

Harmon H. Davis, Barry A. Siegel, J. Heinrich Joist, W. Andrew Heaton, Carla J. Mathias, Laurence A. Sherman, Michael J. Welch

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Abstract

Accumulation of autologous platelets labelled with indium-111 at sites of atherosclerosis or venous thrombosis was demonstrated by scintigraphy in three patients. The lesions detected were bilateral ulcerated carotid-artery plaques, iliofemoral venous thrombosis, and renal-vein thrombosis. This technique shows promise as a non-invasive means of diagnosing focal atherosclerotic and thrombotic lesions.

Original languageEnglish
Pages (from-to)1185-1187
Number of pages3
JournalThe Lancet
Volume311
Issue number8075
DOIs
StatePublished - Jun 3 1978

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    Davis, H. H., Siegel, B. A., Heinrich Joist, J., Heaton, W. A., Mathias, C. J., Sherman, L. A., & Welch, M. J. (1978). SCINTIGRAPHIC DETECTION OF ATHEROSCLEROTIC LESIONS AND VENOUS THROMBI IN MAN BY INDIUM-111-LABELLED AUTOLOGOUS PLATELETS. The Lancet, 311(8075), 1185-1187. https://doi.org/10.1016/S0140-6736(78)90972-8