Schizophrenia and substance use comorbidity: A genome-wide perspective

Renato Polimanti, Arpana Agrawal, Joel Gelernter

Research output: Contribution to journalComment/debate

6 Scopus citations


Dual diagnosis with substance use disorders (SUDs) consistently contributes to the premature mortality and increased disability observed in schizophrenia. Large genome-wide association studies are providing the information needed to investigate the genetic architecture of psychiatric disorders. Here, we discuss recent genetic investigations of dual diagnosis (i.e., schizophrenia plus a SUD) and how these findings can inform public health messages.

Original languageEnglish
Article number25
JournalGenome medicine
Issue number1
StatePublished - Mar 21 2017

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