@article{1bce8580c30f46b4a9a2f55d4acca7ef,
title = "Scaffold-Based Therapies: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle",
abstract = "Background: The evidence supporting best practice guidelines in the field of cartilage repair of the ankle are based on both low quality and low levels of evidence. Therefore, an international consensus group of experts was convened to collaboratively advance toward consensus opinions based on the best available evidence on key topics within cartilage repair of the ankle. The purpose of this article is to report the consensus statements on “Scaffold-Based Therapies” developed at the 2017 International Consensus Meeting on Cartilage Repair of the Ankle. Methods: Seventy-five international experts in cartilage repair of the ankle representing 25 countries and 1 territory were convened and participated in a process based on the Delphi method of achieving consensus. Questions and statements were drafted within 11 working groups focusing on specific topics within cartilage repair of the ankle, after which a comprehensive literature review was performed and the available evidence for each statement was graded. Discussion and debate occurred in cases where statements were not agreed upon in unanimous fashion within the working groups. A final vote was then held, and the strength of consensus was characterized as follows: consensus, 51% to 74%; strong consensus, 75% to 99%; unanimous, 100%. Results: A total of 9 statements on scaffold-based therapies reached consensus during the 2017 International Consensus Meeting on Cartilage Repair of the Ankle. One achieved unanimous support, 8 reached strong consensus (greater than 75% agreement), and 1 was removed because of redundancy in the information provided. All statements reached at least 80% agreement. Conclusions: This international consensus derived from leaders in the field will assist clinicians with applying scaffold-based therapies as a treatment strategy for osteochondral lesions of the talus. Level of Evidence: Level V, expert opinion.",
keywords = "ACI, AMIC, MACI, ankle, osteochondral lesion, scaffold, talus",
author = "{the International Consensus Group on Cartilage Repair of the Ankle} and Rothrauff, {Benjamin B.} and Murawski, {Christopher D.} and Chayanin Angthong and Christoph Becher and Stefan Nehrer and Philipp Niemeyer and Martin Sullivan and Victor Valderrabano and Markus Walther and Ferkel, {Richard D.} and Jakob Ackermann and Adams, {Samuel B.} and Andrews, {Carol L.} and Batista, {Jorge P.} and Baur, {Onno L.} and Steve Bayer and Berlet, {Gregory C.} and Boakye, {Lorraine A.T.} and Brown, {Alexandra J.} and Roberto Buda and Calder, {James D.F.} and Canata, {Gian Luigi} and Carreira, {Dominic S.} and Clanton, {Thomas O.} and Jari Dahmen and Pieter D{\textquoteright}Hooghe and DiGiovanni, {Christopher W.} and Dombrowski, {Malcolm E.} and Drakos, {Mark C.} and Ferrao, {Paulo N.F.} and Fortier, {Lisa A.} and Mark Glazebrook and Eric Giza and Mohamed Gomaa and Simon G{\"o}rtz and Haleem, {Amgad M.} and Kamran Hamid and Laszlo Hangody and Hannon, {Charles P.} and Daniel Haverkamp and Jay Hertel and Beat Hintermann and Hogan, {Ma Calus V.} and Hunt, {Kenneth J.} and Hurley, {Eoghan T.} and J{\'o}n Karlsson and Kearns, {Stephen R.} and Kennedy, {John G.} and Kerkhoffs, {Gino M.M.J.} and Kim, {Hak Jun} and Kong, {Siu Wah} and Labib, {Sameh A.} and Lambers, {Kaj T.A.} and Lee, {Jin Woo} and Lee, {Keun Bae} and Ling, {Jeffrey S.} and Longo, {Umile Giuseppe} and Alberto Marangon and Graham McCollum and Mitchell, {Adam W.} and Mittwede, {Peter N.} and Nunley, {James A.} and O{\textquoteright}Malley, {Martin J.} and Osei-Hwedieh, {David O.} and Jochen Paul and Pearce, {Christopher J.} and Helder Pereira and Adam Popchak and Prado, {Marcelo P.} and Raikin, {Steven M.} and Reilingh, {Mikel L.} and Schon, {Lew C.} and Yoshiharu Shimozono and Helene Simpson and Smyth, {Niall A.} and Sofka, {Carolyn M.} and Pietro Spennacchio and Stone, {James W.} and Masato Takao and Yasuhito Tanaka and Thordarson, {David B.} and Rocky Tuan and {van Bergen}, {Christiaan J.A.} and {van Dijk}, {C. Niek} and {van Dijk}, {Pim A.D.} and Francesca Vannini and Tanawat Vaseenon and Martin Wiewiorski and Xiangyang Xu and Youichi Yasui and Hua Yinghui and Ichiro Yoshimura and Younger, {Alastair S.E.} and Zijun Zhang",
note = "Publisher Copyright: {\textcopyright} 2018, The Author(s) 2018.",
year = "2018",
month = jul,
day = "1",
doi = "10.1177/1071100718781864",
language = "English",
volume = "39",
pages = "41S--47S",
journal = "Foot and Ankle International",
issn = "1071-1007",
number = "1_suppl",
}