Abstract
Sarcoplasmic reticulum ATPase has been found to cleave the ATP analog adenyl-5'-yl imidodiphosphate in a calcium-dependent reaction. The reaction products were determined by 31P NMR to be inorganic phosphate and adenyl-5'-yl phosphoramidate (AMP-PN). AMP-PNP hydrolysis, like ATP hydrolysis, drives active Ca2+ accumulation by sarcoplasmic reticulum vesicles.
| Original language | English |
|---|---|
| Pages (from-to) | 9793-9795 |
| Number of pages | 3 |
| Journal | Journal of Biological Chemistry |
| Volume | 256 |
| Issue number | 19 |
| State | Published - Oct 10 1981 |