Same Day Discharge is a Successful Approach for the Majority of Patients Undergoing Holmium Laser Enucleation of the Prostate

Deepak K. Agarwal, Tim Large, Yan Tong, Christa L. Stoughton, Erica M. Damler, Charles U. Nottingham, Marcelino E. Rivera, Amy E. Krambeck

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Background: Limited research has focused on success with hospital discharge on the same day of surgery after holmium laser enucleation of the prostate (HoLEP). Objective: To determine the success of same-day discharge in our HoLEP cohort and factors associated with this approach. Design, setting, and participants: A retrospective review of our prospectively maintained HoLEP database demonstrated that 473 adult males underwent HoLEP from July 2018 to December 2019 at a tertiary referral center and high-volume HoLEP hospital. Patients were divided into groups according to planned inpatient admission (PIA), successful same-day discharge (SDD), or unplanned admission (UA). Outcome measurements and statistical analysis: The PIA, SDD, and UA groups were assessed for differences in preoperative demographic data, perioperative surgical data, and postoperative follow-up data. SDD and UA were then compared to determine if any specific factors predicted UA, including univariate and multivariate logistic regression analyses. Results and limitations: Age (p = 0.0049), use of anticoagulation (p = 0.037), American Society of Anesthesiologists score of 3–4 (p = 0.0017), and enucleation time (p=0.0178) were significantly higher in the PIA group. Morcellation time (p = 0.0059) and the rate of bedside catheter irrigation (p = 0.04) were higher in the UA group. The SDD group had the highest rate of successful voiding trial (p = 0.0001). Among the three groups, there was no difference in the rate of postoperative complications (p = 0.141). In a comparison of the SDD and UA groups, morcellation time (p = 0.041), the rate of bedside clot evacuation (p = 0.004), and successful voiding trial (p = 0.003) all favored SDD. There was no difference in 90-d complications (p = 0.536). A limitation is the retrospective nature of this study. Conclusions: HoLEP can be successfully performed as day surgery without an increase in postoperative complications. HoLEP as day surgery is possible for any patient who does not require admission for medical comorbidities. Patient summary: Same-day discharge (SDD) after holmium laser enucleation of the prostate (HoLEP) is possible and is successful in 87.4% of patients. Patients with longer morcellation times and with post-procedure hematuria with clots are more likely to have an unplanned admission. Use of a 120-W modulated-pulse laser resulted in a higher rate of SDD success. The culture change to day surgery is time-intensive owing to education of the postsurgical care units and clinic staff, and in our experience took approximately 9 mo to seamlessly integrate SDD as our HoLEP standard of care.

Original languageEnglish
Pages (from-to)228-234
Number of pages7
JournalEuropean Urology Focus
Issue number1
StatePublished - Jan 2022


  • Anticoagulation
  • Benign prostatic hyperplasia
  • Holmium laser
  • Holmium laser enucleation of the prostate
  • Outcomes
  • Prostate enucleation
  • Same day surgery


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