Salvage laryngectomy following organ-preservation therapy – An evidence-based review

Dustin A. Silverman; Sidharth V. Puram; James W. Rocco; Matthew O. Old; Stephen Y. Kang

doi:10.1016/j.oraloncology.2018.11.022

Salvage laryngectomy following organ-preservation therapy – An evidence-based review

Dustin A. Silverman, Sidharth V. Puram, James W. Rocco, Matthew O. Old, Stephen Y. Kang

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.

Original language	English
Pages (from-to)	137-144
Number of pages	8
Journal	Oral Oncology
Volume	88
DOIs	https://doi.org/10.1016/j.oraloncology.2018.11.022
State	Published - Jan 2019

Keywords

Complications
Elective neck dissection
Free flap reconstruction
Locoregional flaps
Organ preservation
Pharyngocutaneous fistula
Prognostic factors
Salvage laryngectomy
Survival rates

Access to Document

10.1016/j.oraloncology.2018.11.022

Cite this

@article{710a695f292b4727ab5f35e7864b1baa,

title = "Salvage laryngectomy following organ-preservation therapy – An evidence-based review",

abstract = "Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.",

keywords = "Complications, Elective neck dissection, Free flap reconstruction, Locoregional flaps, Organ preservation, Pharyngocutaneous fistula, Prognostic factors, Salvage laryngectomy, Survival rates",

author = "Silverman, {Dustin A.} and Puram, {Sidharth V.} and Rocco, {James W.} and Old, {Matthew O.} and Kang, {Stephen Y.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2019",

month = jan,

doi = "10.1016/j.oraloncology.2018.11.022",

language = "English",

volume = "88",

pages = "137--144",

journal = "Oral Oncology",

issn = "1368-8375",

}

TY - JOUR

T1 - Salvage laryngectomy following organ-preservation therapy – An evidence-based review

AU - Silverman, Dustin A.

AU - Puram, Sidharth V.

AU - Rocco, James W.

AU - Old, Matthew O.

AU - Kang, Stephen Y.

PY - 2019/1

Y1 - 2019/1

N2 - Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.

AB - Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.

KW - Complications

KW - Elective neck dissection

KW - Free flap reconstruction

KW - Locoregional flaps

KW - Organ preservation

KW - Pharyngocutaneous fistula

KW - Prognostic factors

KW - Salvage laryngectomy

KW - Survival rates

UR - http://www.scopus.com/inward/record.url?scp=85057329516&partnerID=8YFLogxK

U2 - 10.1016/j.oraloncology.2018.11.022

DO - 10.1016/j.oraloncology.2018.11.022

M3 - Article

C2 - 30616784

AN - SCOPUS:85057329516

SN - 1368-8375

VL - 88

SP - 137

EP - 144

JO - Oral Oncology

JF - Oral Oncology

ER -

Salvage laryngectomy following organ-preservation therapy – An evidence-based review

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this