Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated with Posaconazole

Patrick Reich, Thomas Shute, Colleen Lysen, Shawn R. Lockhart, M. Kelly Keating, Philip Custer, Rachel Orscheln

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


An 11-year-old immunocompetent girl presented with two and a half months of progressive right orbital cellulitis, which did not respond to multiple courses of antibiotics or prednisone. A panfungal polymerase chain reaction primer was positive for Saksenaea vasiformis, and she completed 5 months of oral posaconazole therapy after debridement. Saksenaea vasiformis is a rare cause of zygomycosis, and it typically causes skin and soft tissue infection in immunocompetent hosts, particularly after a traumatic injury. The diagnosis should be considered in cases with a protracted course that fail to respond to typical antibiotic therapy. Treatment includes surgical debridement, in additional to antifungal therapy with amphotericin B or posaconazole.

Original languageEnglish
Pages (from-to)E169-E171
JournalJournal of the Pediatric Infectious Diseases Society
Issue number3
StatePublished - Sep 1 2018


  • Saksenaea vasiformis
  • fungus
  • orbital cellulitis
  • posaconazole
  • zygomycete


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