Sacrococcygeal teratomas: Prenatal surveillance, growth and pregnancy outcome

R. Douglas Wilson, Holly Hedrick, Alan W. Flake, Mark P. Johnson, Michael W. Bebbington, Stephanie Mann, Jack Rychik, Kenneth Liechty, N. Scott Adzick

Research output: Contribution to journalArticlepeer-review

99 Scopus citations

Abstract

Objective: Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment. Methods: Retrospective review of 23 fetuses with SCT: prenatal diagnosis, surveillance, delivery, and early postnatal outcome are reported. Results: Cardiac output failure physiology requires serial evaluation. The size of the SCT determines obstetrical risks and mode of delivery. An SCT growth rate approaching >150 cm3 per week may be associated with increased perinatal mortality risks. Maternal morbidity is related mainly to polyhydramnios and preterm labor. Conclusions: Perinatal mortality is approximately 43%. Maternal-fetal surgery for fetal physiologic deterioration is not frequent, but serial surveillance is required to minimize fetal morbidity/mortality and maternal morbidity. Rapid SCT growth rates may be associated with increased risk of perinatal mortality.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalFetal Diagnosis and Therapy
Volume25
Issue number1
DOIs
StatePublished - Aug 2009

Keywords

  • Outcome
  • Prenatal
  • Sacrococcygeal teratomas
  • Surveillance
  • Teratoma growth

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