Running to stand still: BCR-like signaling suppresses type I IFN responses in pDC

Melissa K. Swiecki; Marco Colonna

doi:10.1002/eji.200737944

Running to stand still: BCR-like signaling suppresses type I IFN responses in pDC

Melissa K. Swiecki
, Marco Colonna

Research output: Contribution to journal › Comment/debate

6 Scopus citations

Abstract

Plasmacytoid dendritic cells (pDC) specialize in the secretion of type I interferon (IFN). Although multiple pathways that modulate type I IFN responses have been described they are inadequately defined. In this issue of the European Journal of Immunology, evidence for a B cell receptor (BCR)-like signaling cascade in pDC that suppresses type I IFN production is provided.

Original language	English
Pages (from-to)	3327-3329
Number of pages	3
Journal	European Journal of Immunology
Volume	37
Issue number	12
DOIs	https://doi.org/10.1002/eji.200737944
State	Published - Dec 2007

Keywords

Signaling
Signalosome
Type 1 IFN
pDC

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10.1002/eji.200737944

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title = "Running to stand still: BCR-like signaling suppresses type I IFN responses in pDC",

abstract = "Plasmacytoid dendritic cells (pDC) specialize in the secretion of type I interferon (IFN). Although multiple pathways that modulate type I IFN responses have been described they are inadequately defined. In this issue of the European Journal of Immunology, evidence for a B cell receptor (BCR)-like signaling cascade in pDC that suppresses type I IFN production is provided.",

keywords = "Signaling, Signalosome, Type 1 IFN, pDC",

author = "Swiecki, \{Melissa K.\} and Marco Colonna",

year = "2007",

month = dec,

doi = "10.1002/eji.200737944",

language = "English",

volume = "37",

pages = "3327--3329",

journal = "European Journal of Immunology",

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TY - JOUR

T1 - Running to stand still

T2 - BCR-like signaling suppresses type I IFN responses in pDC

AU - Swiecki, Melissa K.

AU - Colonna, Marco

PY - 2007/12

Y1 - 2007/12

N2 - Plasmacytoid dendritic cells (pDC) specialize in the secretion of type I interferon (IFN). Although multiple pathways that modulate type I IFN responses have been described they are inadequately defined. In this issue of the European Journal of Immunology, evidence for a B cell receptor (BCR)-like signaling cascade in pDC that suppresses type I IFN production is provided.

AB - Plasmacytoid dendritic cells (pDC) specialize in the secretion of type I interferon (IFN). Although multiple pathways that modulate type I IFN responses have been described they are inadequately defined. In this issue of the European Journal of Immunology, evidence for a B cell receptor (BCR)-like signaling cascade in pDC that suppresses type I IFN production is provided.

KW - Signaling

KW - Signalosome

KW - Type 1 IFN

KW - pDC

UR - https://www.scopus.com/pages/publications/37549045597

U2 - 10.1002/eji.200737944

DO - 10.1002/eji.200737944

M3 - Comment/debate

C2 - 18050162

AN - SCOPUS:37549045597

SN - 0014-2980

VL - 37

SP - 3327

EP - 3329

JO - European Journal of Immunology

JF - European Journal of Immunology

IS - 12

ER -

Running to stand still: BCR-like signaling suppresses type I IFN responses in pDC

Abstract

Keywords

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